In 1054, however, the argument contributed to the [[Great Schism]] of the East and West, and the West went so far as to accuse the East of heresy for not including the ''filioque'' in the Creed. There were many other issues involved, in large part based on misunderstandings between Greek and Latin traditions, as well as the irascible temperament of the antagonists. These were Cardinal [[Humbert of Silva Candida|Humbert]] from Rome and Patriarch [[Michael I Cerularius of Constantinople|Michael Cerularius]] of Constantinople. In addition to the actual difference in wording and doctrine in the ''filioque'', a related issue was the right of the Pope to make a change in the [[Nicene-Constantinopolitan Creed]] on his own, apart from an [[Ecumenical Council]].