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Patriarch Jeremias was a native of Zitsa in Epirus. The details of his early life are unknown. HIs education was limited, but he excelled in management. He became [[Archbishop]] of Sofia about the year 1513, if not earlier.
He was elected to the [[cathedra]] of Constantinople on [[December 31]], 1522. After his installation Patr. Jeremias began a round of visits to Cyprus, Egypt, [[Church of Sinai|Sinai]] and Palestine. In the Spring of 1524, a group of [[clergy]] and notables of Constantinople [[deposition|deposed]] him and elected in his place [[Joannicius I of Constantinople|Joannicius]] the Metropolitan of Sozopolis. Upon receiving the news of his deposition, Patr. Jeremias called, in [[Jerusalem]], a [[synod]] with the [[patriarch]]s of Jerusalem, Antioch, and Alexandria that [[excommunication|excommunicated]] Joannicius. Upon Patr. Jeremias' return from Jerusalem, Sultan Suleiman the Magnificant ordered him to be re-installed as patriarch. This took place in Constantinople on [[September 24]], 1525.
In 1537, Patr. Jeremias obtained from the Sultan Suleiman the Magnificent an order to stop the conversion of [[church]]es into mosques in Constantinople. However, after Suleiman's death in 1566 this decision was not continued by his successors.