In 1975, Metr. Nicholas enrolled as a graduate student at the [[Holy Cross Greek Orthodox School of Theology (Brookline, Massachusetts)|Holy Cross Greek Orthodox School of Theology]] in Brookline, Massachusetts. In 1978 he earned a Masters of Divinity degree and was the valedictorian of his class. He continued academic work through post-graduate studies at the University of Athens following his graduation from Holy Cross.
His Eminence worked in public health for ten years in Denver, where he was active in the life of the Assumption Greek Orthodox Cathedral. In 1983, he joined the Greek Orthodox Diocese of Denver, working as an assistant to Bishop [[Philip of Atlanta|Philip of Daphnousia]], who was serving as ''[[locum tenens]]'' of the Diocese. Later, he served Bishop [[Anthimos (
Draconakis) of Denver|Anthimos of Denver]] as an assistant. In 1990, he formally began his service in the Diocese of Pittsburgh as Administrative Assistant to Bishop [[Maximos (Aghiorgoussis) of Pittsburgh|Maximos]].
Metr. Nicholas was [[ordination|ordained]] a [[deacon]] on [[July 6]], 1991, by Bishop Maximos at the Annunciation Church in Mckeesport, Pennsylvania. He was ordained to the [[priest]]hood by Bishop Maximos and co-celebrant Bishop Philip at the Assumption Greek Orthodox Cathedral in Denver, Colorado, on [[July 23]], 1991. He was elevated to the rank of [[Archimandrite]] on the same day, based on his years of service to the Church.