Alexis or Alexios may refer to any of the following saints:
- Alexios, Archbishop of Cyprus
- Alexis, Archbishop of Moscow (February 12 and October 5)
- Alexios the Man of God (March 17)
- Alexios the hermit of the Kiev Caves (April 24)
- Alexios, Bishop of Bithynia (June 10)
- Alexius, martyr of Constantinople (August 9)
- Alexis (Toth) of Wilkes-Barre (May 7)
- Alexis (Kabaliuk) of Carpathia (October 21 and December 2)
There are also bishops with this name:
- Alexis van der Mensbrugghe (1899-1980)
- Patriarch Alexei II (Ridiger) of Moscow