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holy Bishop Jacob died peacefully in Nisibis, according to some in A.D. 338,<ref>Christian Classics Ethereal Library (CCEL). ''[http://www.ccel.org/s/schaff/encyc/encyc06/htm/iii.lv.xvi.htm JACOB (JAMES) OF NISIBIS].''</ref><ref name="ASOC"/><ref name="SOCA"/> and according to others in A.D. 350.<ref name="BARTLEBY"/><ref name="SMITH"/>
He was honourably interred within the city, in pursuance, it is said, of an express charge of [[Constantine the Great]] to his son Constantius, indicative of the reverance he held for him, that after death his [[Relics|hallowed remains]] might continue to defend Nisibis against its enemies.