St. Macrina was born to a holy family: her parents were Ss. [[Basil the Elder]] and [[Emily]]; four of her nine brothers and sisters are commemorated as saints: [[Basil the Great]], [[Peter of Sebaste]], [[Gregory of Nyssa]], and [[Theosebia the Deaconess]]; her grandmother, for whom she was named, is commemorated as St. [[Macrina the Elder]].
After her siblings grew up, she convinced her mother to take [[monastic]] vows with her. Following her mother's death, she led the [[nun]]s in the [[monastery]]. She died in 379/380 and was buried in a grave shared with her parents, with a eulogy by her younger brother, St. Gregory. He also wrote ''The Life of St. Macrina''.
[[Troparion]] (Tone 8) [http://oca.org/FStropars.asp?ID=102055]
:The [[icon|image]] of God was truly preserved in you, O Mother,
:For you took up the [[
Holy Cross|Cross]] and followed [[Christ]].
:By so doing, you taught us to disregard the flesh, for it passes away,
:But to care instead for the soul, since it is immortal.
*[http://ocafs.oca.org/FeastSaintsViewer.asp?FSID=102055 Venerable Macrina the Sister of St Basil the Great] ([[OCA]])
/en/chapel/ saints.asp?contentid=133 Macrina the Righteous, sister of St. Basil] ([[GOARCH]]) *[http://www.midiowa.com/ssephmac/Macrina.htm About St. Macrina]
*[http://www.fordham.edu/halsall/basis/macrina.html#life ''The Life of Saint Macrina''] a translation of the work by St. Gregory of Nyssa (Medieval Sourcebook)
www. orthodoxresearchinstitute.org/ resources/ saints/ fourth_century_saint.htm "A Fourth-Century Saint for Our Times"] from ''Again Magazine'', a publication of the [[Antiochian Orthodox Christian Archdiocese of North America]]. September 1994, p. 3. *[http://www.comeandseeicons.com/m/phn67.htm Icon and Story of St. Macrina]